This is what I really wanted to know.
Maybe im not being detailed enough in my typing, here are(or were) my intentions. I do tend to be unorganized when I type out my ideas in a rush, sorry about that.
Space is not so much the issue here, im really concerned about moving.
1.) Move my most used software to external hard drive ready to be moved to main OS drive. (which I'v done with games and other software from my program files in c:/ but not so much music related things on a small flash drive.)
2.) leave a good half of my sample library on this current pc.
3.) if possible, keep vst's on drive, but as you said, I should keep things like that on my main OS drive, which is the new pc I am moving too soon.
sorry for the poor typing.