I can see it now. Godly fast shredding, with piano coming out of your amp instead of normal guitar tone. Actually, I've used a midi guitar at guitar center once and it actually worked much better than I thought, it easily picked up some quick riffs as if it wasn't a problem. Though I didn't try shredding.
However, if you're REALLY good with guitar (and I mean it), I think throwing on a MIDI interface would be worth it. Granted, you can get a midi controller for way cheaper.
Here's what you would need if you wanted to go MIDI guitar:
http://guitars.musiciansfriend.com/product/Roland-GI20-GKMIDI-Interface-?sku=150094
http://accessories.musiciansfriend.com/product/Roland-GK3-Guitar-Pickup?sku=700379
I have XHTML and some JS experience, and I would definitely open for doing this, as I no longer do JS code modifications for message boards. What would you need done?