No one's pointed out that Reason is the only one not compatible with VSTs but anyway, Skewered Logic has nailed this. Protools isn't good for MIDI sequencing, in fact, it's terribad. That being said, there's no better DAW for use in the studio; perfect for live users who just want to record something and chop it up. I'm an FL user and I must say that FL is more than capable of recording both MIDI and live input (a single source at a time though), if you were considering going with that.
It might be worth hitting up some of the other DAW's demos to see if you prefer the flow. You could try:
Protools (Full version is OSX only)
FL Studio
Reason (no vst support)
Cubase
Sonar
Ableton Live
Reaper ("Free", you can carry on using it after the trial period.)
Logic (OSX only)
There are some others, but these are the big ones.