If they did that, there wouldn't be many villians left. The game and movies are seperate. The Lizard is probably up for the next film, but he also appeared in a game already.
I'm having two thoughts about an eventual reappearance of Venom. I'd love to see him the way he should be with enough screen-time, wicked voice and big posture. That said, it's a little lame to make another move about Venom. He was the big crowd-puller for this movie and they can't do the same trick twice (well they can, but it'd be lame).
Let them keep the cast for now, get the scriptwriter from the first film back (forgot the name and I'm too lazy to look it up)and then we'll see about villians and stuff. Also, put a Black Cat in the movie, that's always good to look at