So people spend thousands on guitars and amps and all sorts of stuff trying to get a better tone, and almost uniformly spent 50c on a cruddy piece of plastic which is the actual thing exciting the string. This, imo, is stupid. I did a bunch of research on the options and came across Red Bear.
These guys use proteins to culture a turtle shell substitute which is pretty much the perfect pick material. I cannot describe how easily these things glide across strings. I feel like I'm putting in absolutely no effort and I'm playing substantially faster and with more control then ever before. Anything that can make me super excited about just playing anything on my guitar after like 8 years of playing has gotta be special.
I used to use a Jazz III, which is about 1.4mm, pretty awesome lead pick. This is a picture of it next to my Red Bear lil' Jazzer pick.
It's about 1.6mm, super pointy, and with a really nice feeling edge to it. The holes are there to make it easier to grip. I should probably mention they cost $20 a crack ($25 with your name on it) but they last for ages. Here's guthrie govan if you need any more proof these are epic and that you should buy one:
I know of a bunch of other manufacturers of more 'premium' picks. What do you guys use? And if you just use boring brand X picks, I urge you to experiment with materials as well as with shapes and sizes.