I don't see a reason why it would and it's the first I've heard of it. FL also has a VST plugin if you want to use it in another DAW.
Also curious why you want to use Cubase with FL? Rewire was mostly a workaround for the limitations of programs like Reason, for modern DAWs it seems to me that they're all capable enough where using them simultaneously isn't that worthwhile.
On the subject of FL is it true Rewire can downgrade the quality of other DAWs? Down the track I wanna get Cubase, Vocaloid and Super Audio Kart and use them with FL, but not if it will downgrade the sound quality.