Well, the DS is getting it's share of unusual games with tons of charisma. Elite Beat Agents and Phoenix Wright come to mind, along with the upcoming Square game It's a Wonderful Life. And now this, Hotel Dusk: Room 215. It's noir-like mystery game and, pretty much all the info on it is in the quote below. It seems to be coming out on the 22nd in the US. Is this a "more serious Phoenix Wright" endeavour, poised for sucess? Or something not as spectacular, like Trace Memory? Who knows, but here's a japanese trailer and damn does it look good.
http://www.nintendo.co.jp/ds/awij/player.html?mv=movie_3d&width=626&height=430