Soul Calibur. (SC2 or 3 are the best examples IMO)
Excellent beautiful music, but I've never really felt that it matches up with the gameplay quite well. I think it's much too epic for the simple one-on-one fights that SC has. As each fight begins, a frantic and beautiful score sets up this epic atmosphere, and then two warriors calmly take fighting stances and battle upon a sparse, hazard-less stage.
Fable's music also felt terribly out of place at some points. The Oakvale music is way too Edward Scissorhand's-ish to be a simple village theme. The sweeping choir and orchestra paints a much more vivd and mystical picture than just a simple farming village. And the Arena music left me wanting more of a frantic battle feel. Instead it just came across as sort of brooding, but not exciting. They're both fantastic pieces, but if you compare what's happening in the game to what's happening in the songs, they don't quite match up.